OT 6052: Neurodegenerative

Which of the following is a hallmark characteristic of progressive neurodegenerative diseases like Alzheimer’s disease, Parkinson’s disease, and Multiple Sclerosis?

• Sudden onset of symptoms

• Gradual and irreversible decline in cognitive, motor, and functional abilities

• Episodic exacerbations with complete recovery

• Improvement of symptoms with pharmaceutical interventions

In Parkinson’s Disease, which of the following motor symptoms most significantly affects a client’s ability to engage in self-care activities like dressing and grooming?

• Dysphagia

• Resting tremor

• Bradykinesia

• Hypertonia

In progressive neurodegenerative diseases, occupational therapy interventions are typically aimed at slowing disease progression rather than managing the symptoms and maximizing functional independence.

• True

• False

Parkinson’s Disease can result in significant limitations in activities of daily living (ADLs), but therapy interventions can help improve motor control and minimize freezing episodes, allowing clients to maintain some independence for a longer period.

• True

• False

Which of the following statements best describes the progression of Multiple Sclerosis (MS)?

• It is a progressive disease with continuous decline in function without periods of remission.

• MS is characterized by relapsing-remitting episodes followed by periods of remission.

• The disease progresses only in the later stages, with no early symptoms.

• It primarily affects the peripheral nervous system rather than the central nervous system.

In Parkinson’s Disease, which of the following is most commonly associated with the motor symptoms of the disease?

• Degeneration of the basal ganglia and a deficiency in dopamine production

• Amyloid plaque buildup in the cerebral cortex

• Decreased myelin production in the spinal cord

• Damage to the frontal lobe affecting executive function

Which of the following is a characteristic symptom of Amyotrophic Lateral Sclerosis (ALS)?

• Muscle weakness and atrophy without cognitive impairment

• Severe tremors and rigidity in the early stages

• Chronic, progressive difficulty swallowing due to cognitive decline

• Episodic periods of severe fatigue and shortness of breath

Amyotrophic Lateral Sclerosis (ALS) affects only the upper motor neurons, resulting in purely motor symptoms like spasticity and hyperreflexia.

• True

• False

MS is characterized by the degeneration of neurons in the basal ganglia.

• True

• False

Early symptoms of ALS include muscle weakness, particularly in the respiratory muscles, and a decrease of voluntary movements with slowness of activation.

• True

• False