Chapter 10 Quiz

What is the primary immunologic mechanism responsible for Type I hypersensitivity reactions?

• IgM antibodies

• IgE antibodies

• CD8+ T cells

• Immune complexes

Which cells are primarily involved in the degranulation process during Type I hypersensitivity?

• Dendritic cells

• T cells

• Mast cells

• Erythrocytes

Which cytokine is critical for class switching to IgE production in B cells?

• IL-4

• IL-2

• IL-17

• IFN-γ

What triggers mast cell degranulation in Type I hypersensitivity?

• Cross-linking of IgE by allergens

• Activation of T cells

• Complement activation

• Binding of antibodies to immune complexes

Which of the following is an example of a localized Type III hypersensitivity reaction?

• Systemic lupus erythematosus

• Arthus reaction

• Hemolytic anemia

• Anaphylaxis

What type of antigen is typically involved in Type III hypersensitivity reactions?

• Soluble antigens

• Cell-bound antigens

• Intracellular antigens

• Lipid antigens

What is the primary mediator of tissue damage in Type IV hypersensitivity?

• Antibodies

• Complement proteins

• Cytokines from T cells

• Immune complexes

Which hypersensitivity type is involved in the pathophysiology of Myasthenia Gravis?

• Type I

• Type II

• Type III

• Type IV

Which of the following mediators contributes to bronchoconstriction during an allergic reaction?

• Histamine

• IL-4

• Perforins

• C5a

What is the function of omalizumab in treating allergies?

• Blocks IL-4 signaling

• Inhibits mast cell degranulation

• Neutralizes IgE antibodies

• Suppresses T cells