Obesity

T/F. Obesity is classified as a disease by major health organizations, including the American Medical Association and the World Health Organization.

• True

• False

Which of the following BMI categories is appropriately labeled?

• Normal weight: 16.5-29.9 kg/m2

• Obesity class 1: 30-34.9 kg/m2

• Obesity class 2: 45-49.9 kg/m2

• Obesity class 3: ≥50 kg/m2

All of the following medications increase the risk of weight gain except:

• Insulin

• Paroxetine

• Fluoxetine

• Mirtazapine

Which of the following is a key component of a weight-loss plan for the treatment of obesity?

• High-protein, high-fat diet

• Increase in calorie intake without exercise

• Balanced, calorie-controlled diet with regular exercise

• Strict fasting regimen with rigorous exercise

SG is a 32 YOF inquiring about weight loss medications as she wants to look her best for her sister's wedding in 3 months. BMI: 27.5 kg/m2; PMH: OSA, seasonal allergies. She has recently lost 10 pounds on her own with diet and exercise but would like to lose another 10 before the wedding. She is willing to pay out of pocket for a cheap medication. What is the best recommendation at this time?

• Phentermine 18.75 mg daily

• Semaglutide 0.25 mg weekly

• Bupropion ER-Naltrexone 8-90 mg daily

• Tirzepatide 2.5 mg weekly

Which of the following is a common side effect of the medication Orlistat?

• Increased blood pressure

• Increased heart rate

• Insomnia

• Flatulence and steatorrhea

Which weight-loss medication is contraindicated in individuals with a history of cardiovascular disease due to increased risk of heart attack and stroke?

• Phentermine-topiramate ER

• Orlistat

• Liraglutide

• Tirzepatide

The following weight loss medications can increase blood pressure, heart rate, and cause dry mouth and constipation except:

• Tenuate

• Phentermine

• Contrave

• Liraglutide

DB is a 64 YOM following up for weight loss management (BMI 33.5%). PMH: T2DM (A1c 9.2%), HTN, dyslipidemia, OA, insomnia. Current meds: insulin glargine 28 units daily, metformin 1000 mg bid, lisinopril 20 mg daily, rosuvastatin 10 mg daily. What is the most appropriate recommendation for weight loss at this time?

• Start tirzepatide 2.5 mg weekly, discontinue insulin glargine

• Start tirzepatide 2.5 mg weekly, assess SMBG and titrate insulin as needed

• Start dulaglutide 0.75 mg weekly, discontinue insulin glargine

• Start tirzepatide 2.5 mg weekly, discontinue metformin

T/F. Medications used to treat obesity are safe and effective for long-term use without the need for lifestyle modifications.

• True

• False