What is hematopoiesis?

• The process of clotting blood

• The development and production of blood cells

• The breakdown of old blood cells

• The circulation of blood through vessels

Where does the majority of hematopoiesis occur in adults?

• Liver

• Spleen

• Bone marrow

• Lymph nodes

What characteristic defines multipotent stem cells?

• Ability to differentiate into all cell types in the body

• Limited to differentiating into closely related lineages

• Can only self-renew but not differentiate

• Only produces red blood cells

What stimulates erythropoiesis?

• Hemoglobin

• Erythropoietin (EPO)

• Cytokines

• Platelets

What is the first site of hematopoiesis during embryonic development?

• Bone marrow

• Liver

• Yolk sac

• Spleen

What occurs during the process of erythropoiesis?

• Increase in cell size

• Decrease in nucleus-to-cytoplasm ratio

• Loss of hemoglobin

• Increase in nucleoli

What is the lifespan of circulating erythrocytes?

• 7-10 days

• 30 days

• 120 days

• 180 days

Which organ assumes hematopoiesis during the second month of fetal life?

• Spleen

• Bone marrow

• Liver

• Thymus

Which stage of erythropoiesis is characterized by the presence of a pyknotic nucleus?

• Pronormoblast

• Basophilic normoblast

• Orthochromatic normoblast

• Reticulocyte

What is the main function of the erythrocyte?

• Produce antibodies

• Transport oxygen and remove carbon dioxide

• Support clotting

• Provide immune defense