HEMA2: PLATELETS PRODUCTIONS, STRUCTURE, AND FUNCTION

Normal value of Platelets in x 10^9 / L

• 150-400

• 122 - 350

• 140-379

• 80-500

Portion of platelet in Circulation

• 1/3

• 1/4

• 2/3

• 1/2

Portion of sequestered platelet in spleen

• 1/4

• 1/3

• 2/3

• 1/8

During splenectomy, circulating platelets are:

• Increased

• Decreased

• Not affected

During splenomegaly, circulating platelets are:

• Increased

• Decreased

• Not affected

Shape of platelets in Citrated Whole Blood

• Biconcave

• Cylindrical and beaded

• Circle

• Circle with pseudopods

Enzyme used in Endothelial Cell Eicosanoid pathway

• Thromboxane Synthase

• Thromboxane

• Prostacyclin Synthase

• Phopholipase C

End product of Endothelial cell eicosanoid Pathway

• Prostaglandin I2

• Thrombocyclin

• Phospholipase C

• IP3-DAG

Eicosanoid Pathway and IP3-DAG are both dependent to:

• G-Proteins

• T-Proteins

• They are both independent

• Thromboxane A2

Select all that apply: Dense Granules

• ATP

• Fibronectin

• Platelet Factor 4

• Serotonin

• ATP