Nucleophilic Substitution Reactions Quiz

What is a nucleophile?

• A species with a positive charge

• A species with an unshared electron pair

• A species that donates protons

• A species that accepts electrons

In an S_N2 reaction, the rate depends on which of the following?

• Only the nucleophile concentration

• Only the substrate concentration

• Both the substrate and nucleophile concentrations

• The solvent used

What type of reaction is characterized by a concerted mechanism?

• S_N2 reaction

• Addition reaction

• S_N1 reaction

• Elimination reaction

Which of the following is a good leaving group?

• Hydroxide ion (OH-)

• Fluoride ion (F-)

• Ammonium ion (NH4+)

• Iodide ion (I-)

What is the order of reactivity of substrates for S_N1 reactions?

• 1° > 2° > 3°

• 3° > 2° > 1°

• 3° > vinyl > 1°

• 2° > 1° > methyl

Which solvent type slows down S_N2 reactions?

• Aqueous solvents

• Protic solvents

• Nonpolar solvents

• Polar aprotic solvents

What is the effect of steric hindrance on S_N2 reactions?

• Only affects the nucleophile

• Has no effect on the reaction rate

• Decreases the reaction rate

• Increases the reaction rate

Which of the following nucleophiles is the strongest?

• Water (H2O)

• Hydroxide ion (OH-)

• Iodide ion (I-)

• Bromide ion (Br-)

What is the primary factor affecting the rate of S_N1 reactions?

• The solvent type

• The leaving group ability

• The nucleophile strength

• The substrate concentration

Which type of carbocation is the most stable?

• Primary carbocation

• Secondary carbocation

• Methyl carbocation

• Tertiary carbocation