Mutations and DNA

A mutation that occurs in the gametes of an organism will most likely be transferred to which of the following?

• the sibling of the organism

• the offspring of the organism

• the other organism living nearby

• the mating partner of the organism

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

A codon chart is shown.

Which of these changes to the DNA triplet 3' GCT 5' will not affect the protein produced? (select all that apply)

• GTT

• TCT

• TCC

• GCA

Tags

NGSS.HS-LS1-1

Sickle-shaped red blood cells result from a mutation in the gene that codes for hemoglobin. This mutation results in sickle-cell anemia. A partial sequence of bases from a normal hemoglobin gene and a sequence that results in sickle-cell anemia are shown below.

​ The type of mutation depicted in this sequence is ​ (a)  

• substitution.
• insertion.
• deletion.
• frameshift.

Tags

NGSS.HS-LS1-1

NGSS.HS-LS3-2

Early-onset Alzheimer's disease affects peope under the age of 65. Less than five percent of people who are diagnosed with Alzheimer's disease have this type. Many cases of early-onset Alzheimer's disease are inherited, a type is known as familial Alzheimer's disease (FAD). Which statement is best supported by this information?

• FAD is the result of a genetic change in one or more chromosomes.

• Natural selection will continue to reduce the incidence of FAD.

• FAD affects only the genes of middle-aged people.

• deletion of one amino acid causes FAD.

Tags

NGSS.HS-LS3-1

NGSS.HS-LS3-2

In the 1960s the molecular biologist George Streisinger developed the strand-slippage hypothesis. Streisinger noticed that mutation occurred in areas of DNA that contained many repeated sequences. When a strand-slippage error occurs, an insertion mutation can result.

Insertion mutation affects the DNA by

(a)   nitrogenous bases.

• adding
• exchanging
• damaging
• deleting

Tags

NGSS.HS-LS3-2