AP Biology Biotechnology

Which of the following covalently connects segments of DNA?

• helicase

• DNA polymerase

• ligase

Which of the following synthesizes short segments of RNA?

• helicase

• DNA polymerase

• primase

The leading and the lagging strands differ in that

• the leading strand is synthesized in the same direction as the movement of the replication fork, and the lagging strand is synthesized in the opposite direction.

• the leading strand is synthesized by adding nucleotides to the 3ʹ end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5ʹ end.

When DNA is compacted by histones into 10 nm and 30 nm fibers, the DNA is unable to interact with proteins required for gene expression. Therefore, to allow for these proteins to act, the chromatin must constantly alter its structure. Which processes contribute to this dynamic activity?

• methylation and phosphorylation of histone tails

• nucleotide excision and reconstruction

The genetic code is essentially the same for all organisms. From this, one can logically assume all of the following except

• a gene from an organism could theoretically be expressed by any other organism.

• all organisms have a common ancestor.

• DNA was the first genetic material.

• the same codons in different organisms usually translate into the same amino acids.

Tags

NGSS.HS-LS4-1

In which of the following actions does RNA polymerase differ from DNA polymerase?

• RNA polymerase can initiate RNA synthesis, but DNA polymerase requires a primer to initiate DNA synthesis.

• RNA polymerase binds to single-stranded DNA, and DNA polymerase binds to double-stranded DNA.

RNA polymerase moves in which direction along the DNA?

• 3ʹ → 5ʹ along the template strand

• 3ʹ → 5ʹ along the coding (sense) strand

What are the coding segments of a stretch of eukaryotic DNA called?

• introns

• exons

Introns are significant to biological evolution because

• their presence allows exons to be shuffled.

• they protect the mRNA from degeneration.

A mutation in which of the following parts of a gene is likely to be most damaging to a cell?

• intron

• exon

Tags

NGSS.HS-LS3-2