Exam 2 Advanced Hematology

How many blast cells in a bone marrow aspirate smear are necessary for a diagnosis of acute myeloid leukemia using the WHO criteria?

• 20%

• 15%

• 25%

• 30%

What cytochemical stain is best for differentiating AML from ALL?

• Alpha-napthyl acetate

• Nonspecific esterase

• Myeoperoxidase

• Periodic acid Schiff

Which peripheral blood morphology is associated with dysmyelopoieisis?

• Hyposegmentation

• Hypogranulation

• Schistocytes

• Presence of Heinz Bodies

Which Leukemia is more common in Children?

• Acute myelomonocytic leukemia

• Acute Lymphoblastic leukemia

• Acute Myelogenous leukemia

• Acute myeloid leukemia with minimal maturation

Which chromosome abnormality is associated with mantle cell lymphoma?

• t(11;14)

• t(16;16)

• t(14;18)

• Trisomy 8

Which of the following pairs of cytochemical stains provide essentially the same information with regard to blast cell identity in acute leukemia cases?

• chloroacetate esterase and Sudan Black B

• acid phosphatase and myeloperoxidase

• Periodic acid-Schiff and alkaline phosphatase

•  

  alpha napthyl acetate esterase and myeloperoxidase

Which of the following is a key marker for Chronic Lymphocytic Leukemia (CLL)?

• CD5+ and CD23+

• CD10+ and BCL2+

• CD19+ and CD20-

• CD15+ and CD30+

Which lymphoma subtype is characterized by Reed-Sternberg cells?

• Diffuse Large B-Cell Lymphoma

• Hodgkin Lymphoma

• Follicular Lymphoma

• Burkitt Lymphoma

Which B-cell neoplasm is associated with an aggressive clinical course and CD10 positivity?

• Chronic Lymphocytic Leukemia

• Burkitt Lymphoma

• Plasma Cell Myeloma

• Mycosis Fungoides

Which of the following phenotypes is characteristic of hairy cell leukemia?

•  

  CD11c+, CD19+, CD103+

•  

  CD3+, CD4+, CD7+

• CD11c+, CD3+, CD10+

• CD13+, CD19+, CD25+