Immunology of nephrotic syndrome

Immunology of nephrotic syndrome

University

8 Qs

quiz-placeholder

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Immunology of nephrotic syndrome

Immunology of nephrotic syndrome

Assessment

Quiz

Other

University

Hard

Created by

R Alz3

Used 1+ times

FREE Resource

8 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which immune cell type is primarily implicated in the pathogenesis of Minimal Change Disease (MCD)?

A) B cells

B) T cells

C) Neutrophils

D) Macrophages

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What cytokine is overproduced in children with Minimal Change Disease?

A) IL-1

B) IL-6

C) IL-13

D) TNF-α

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which complement component is most involved in podocyte damage in membranous nephropathy?

A) C1q

B) C3

C) C4b2a

D) C5b-9

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Anti-phospholipase A2 receptor (Anti-PLA2R) antibodies

are associated with which nephrotic syndrome?

A) Minimal Change Disease

B) Focal Segmental Glomerulosclerosis (FSGS)

C) Membranous Nephropathy

D) IgA Nephropathy

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the main hypersensitivity reaction driving immune complex deposition in nephrotic syndrome?

A) Type I (IgE-mediated)

B) Type II (Antibody-mediated cytotoxicity)

C) Type III (Immune complex-mediated)

D) Type IV (T-cell mediated)

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which of the following is a secondary cause of nephrotic syndrome due to immune dysfunction?

A) Diabetes mellitus

B) Systemic lupus erythematosus (SLE)

C) Amyloidosis

D) Toxemia of pregnancy

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

In diabetic nephropathy, what immune mechanism contributes to kidney damage?

A) Direct podocyte toxicity

B) Activation of the lectin complement pathway

C) Type I hypersensitivity reaction

D) Increased regulatory T-cell activity

8.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What immune marker is commonly seen in Focal Segmental Glomerulosclerosis (FSGS)?

A) IgG and C1q

B) IgM and C3

C) IgA and C5

D) IgE and histamine