
Immunology of nephrotic syndrome

Quiz
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Other
•
University
•
Hard
R Alz3
Used 1+ times
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8 questions
Show all answers
1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
A) B cells
B) T cells
C) Neutrophils
D) Macrophages
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What cytokine is overproduced in children with Minimal Change Disease?
A) IL-1
B) IL-6
C) IL-13
D) TNF-α
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which complement component is most involved in podocyte damage in membranous nephropathy?
A) C1q
B) C3
C) C4b2a
D) C5b-9
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Anti-phospholipase A2 receptor (Anti-PLA2R) antibodies
are associated with which nephrotic syndrome?
A) Minimal Change Disease
B) Focal Segmental Glomerulosclerosis (FSGS)
C) Membranous Nephropathy
D) IgA Nephropathy
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the main hypersensitivity reaction driving immune complex deposition in nephrotic syndrome?
A) Type I (IgE-mediated)
B) Type II (Antibody-mediated cytotoxicity)
C) Type III (Immune complex-mediated)
D) Type IV (T-cell mediated)
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which of the following is a secondary cause of nephrotic syndrome due to immune dysfunction?
A) Diabetes mellitus
B) Systemic lupus erythematosus (SLE)
C) Amyloidosis
D) Toxemia of pregnancy
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
In diabetic nephropathy, what immune mechanism contributes to kidney damage?
A) Direct podocyte toxicity
B) Activation of the lectin complement pathway
C) Type I hypersensitivity reaction
D) Increased regulatory T-cell activity
8.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What immune marker is commonly seen in Focal Segmental Glomerulosclerosis (FSGS)?
A) IgG and C1q
B) IgM and C3
C) IgA and C5
D) IgE and histamine
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