Limb Growth and Development Quiz

What forms the mesenchymal core of limb buds?

• Ectoderm

• Lateral plate mesoderm

• Endoderm

• Neural crest

Which limb develops first during limb bud formation?

• Hind limb

• Neither

• Forelimb

• Both simultaneously

What structure thickens distally to form the Apical Ectodermal Ridge (AER)?

• Ectoderm

• Neural tube

• Mesoderm

• Endoderm

What is the primary pattern of growth in limb development?

• Proximodistal

• Dorsoventral

• Radial

• Anteroposterior

What process ensures bone formation and growth in limbs?

• Morphogenesis

• Differentiation

• Apoptosis

• Ossification

Which of the following is NOT a factor guiding limb morphogenesis?

• TGF-beta

• HOX

• FGF

• SHH

What is the role of apoptosis in limb development?

• Bone formation

• Digit formation

• Joint formation

• Muscle development

Which limb structure is responsible for joint formation?

• Limb buds

• Mesenchymal core

• Apical Ectodermal Ridge

• Ectodermal covering

What type of growth pattern is associated with limb musculature development?

• Anteroposterior

• Proximodistal

• Radial

• Dorsoventral

Which of the following is a key molecular regulator of limb development?

• WNT7a

• BMP

• VEGF

• TGF-beta