Fatty Acid and Lipid Metabolism Quiz

Which of the following lists the four steps of fatty acid synthesis in the correct order?

• Production of acetyl-CoA → Citrate movement into mitochondria → Production of malonyl-CoA → Active fatty acid synthase

• Citrate movement out of mitochondria → Production of acetyl-CoA → Production of malonyl-CoA → Active fatty acid synthase

• Active fatty acid synthase → Production of malonyl-CoA → Citrate movement out of mitochondria → Production of acetyl-CoA

• Production of malonyl-CoA → Production of acetyl-CoA → Active fatty acid synthase → Citrate movement out of mitochondria

Which of the following is an activator of de novo fatty acid synthesis?

• Glucagon

• Epinephrine

• Insulin

• AMP

How many Acetyl-CoA, ATP, and NADPH are required to synthesize an 18-carbon (C18) fatty acid through de novo fatty acid synthesis?

• 9 Acetyl-CoA, 9 ATP, 18 NADPH

• 9 Acetyl-CoA, 8 ATP, 16 NADPH

• 9 Acetyl-CoA, 8 ATP, 14 NADPH

• 9 Acetyl-CoA, 8 ATP, 16 NADPH

Desaturase enzymes can only introduce double bonds between carbon atoms ___ through ___ of a fatty acid.

• 1 and 2

• 2 and 9

• 1 and 12

• 1 and 9

Which two important fatty acids cannot be synthesized in the body and must be obtained from the diet?

• Omega-3 and Omega-6

• Omega-6 and Omega-9

• Omega-3 and Omega-9

• Omega-7 and Omega-9

NSAIDs like aspirin can reduce inflammation by inhibiting the synthesis of __________.

• Leukotrienes

• Phospholipids

• Thromboxanes

• Prostaglandins

Which of the following lipoprotein compositions would correspond to the smallest and most dense lipoprotein?

• Low protein content, high lipid content

• Low protein content, low lipid content

• High protein content, low lipid content

• High protein content, high lipid content

Which enzyme is responsible for rapidly breaking down chylomicrons and VLDL?

• Lipolyse lipase

• Lipoprotein lipase

• Chylomicron lipase

• LDL lipase

After the hydrolysis of their triacylglycerides, chylomicrons and VLDL remnants become enriched with which molecule?

• Cholesterol

• Glucose

• Phospholipids

• Amino acids

Which cofactor is required for the activity of lipoprotein lipase?

• Apo C

• Apo A

• Apo E

• Apo D