QUIZ 2 RBC VARIATIONS PART 2

Microcytosis is defined as RBCs with diameter:

• >9 μm

• 8 μm

Anisocytosis is quantitatively measured by:

• MCH

• MCHC

• RDW

• ESR

Mixed microcytic and macrocytic RBCs will cause:

• Increased RDW

• Decreased RDW

• Low MCHC

• High ESR

Severe anisocytosis suggests:

• Uniform cell size

• High hemoglobin

• Mixed RBC population

• Infections

Poikilocytosis is defined as:

• Variation in RBC size

• Variation in RBC shape

• Low RBC count

• RBC clumping

Tear-drop cells (dacrocytes) are associated with:

• Liver disease

• Megaloblastic anemia

• Myelofibrosis

• Iron deficiency

Spherocytes are typically found in:

• Sickle cell anemia

• Hereditary spherocytosis

• Iron deficiency anemia

• Megaloblastic anemia

Elliptocytes are elongated RBCs often seen in:

• Hereditary elliptocytosis

• Iron overload

• Polycythemia

• Liver disease

Schistocytes are a hallmark of:

• Iron deficiency

• DIC

• Leukemia

• Megaloblastic anemia

Sickle cells are due to:

• Iron deficiency

• Hemoglobin C

• Hemoglobin S polymerization

• Vitamin B12 deficiency