Insulin Analogues Quiz

Which of the following Insulin analogues is/are rapid-acting analog?

• Insulin glargine

• Insulin detemir

• Glulisine

• Insulin Ultralente

• Insulin–protamine complex

Which of the following Insulin analogs contains myristic acid (Fatty acid)?

• Insulin glargine

• Lyspro

• Insulin detemir

• Glulisine

• Ultralente Insulin

Which of the following insulin preparations contains Zn²⁺?

• Insulin glargine

• Lispro

• Insulin–protamine complex

• Glulisine

• Ultralente insulin

Which of the following statements about Insulin glargine is correct?

• Two extra arginine molecules attached at the end of the B chain to increase the isoelectric point

• Two extra arginine molecules attached at the end of the B chain to increase the acidity

• Two extra arginine molecules attached at the end of the B chain to increase the lipophilicity

• Two extra arginine molecules attached at the end of the B chain to promote albumin binding

• Two extra arginine molecules attached at the end of the B chain to decrease the isoelectric point

Which of the following statements about Insulin aspart is/are correct?

• Insulin aspart incorporates an amino-acid change (Pro B28 to Asp) that also creates charge repulsion

• Aspart differs from human insulin in the replacement of the B3 amino acid asparagine with lysine

• Aspart is a long-acting insulin analog

• Aspart is a rapid-acting insulin analog

• A lysine-proline sequence at the end of the insulin B chain reversed

Which of the following compounds is to stimulate the release of insulin from β cells?

• Biguanide

• Sulfonylureas

• α-glucosidase

• Insulin detemir

• Ultralente Insulin

Tags

NGSS.HS-LS1-3

Which of the following compounds is an insulin sensitizer (enhances insulin sensitivity)?

• Biguanide

• Sulfonylureas

• α-glucosidase

• Insulin detemir

• Ultralente Insulin

To which class of compounds does this structure belong?

• Thiazolidinediones

• Biguanides

• Nucleosides

• Carbohydrates

• Sulfonylureas

To which class of compounds does this structure belong?

• Thiazolidinediones

• Biguanides

• Nucleosides

• Carbohydrates

• Sulfonylureas

Tags

NGSS.HS-PS1-2

Which region of the above structure is essential to its activity?

• Region B

• Region C

• Region A

• Region A & C

• Region B & C

Tags

NGSS.HS-LS1-1