MLT478: LEUKAEMIA

What is the primary characteristic of leukaemia?

• Uncontrolled proliferation of red blood cells.

• Decreased of haematopoietic progenitor cells.

• Accumulation of abnormal white blood cells in the bone marrow and blood.

• Increased production of haematopietic progenitor cells.

What does the presence of the structure (arrow) in myeloblasts indicate?

• Acute lymphoblastic leukaemia

• Normal myeloid development

• Acute myeloid leukaemia

• Chronic lymphocytic leukaemia

Which type of leukaemia is characterized by the presence of myeloblasts and promyelocytes?

• Chronic lymphocytic leukaemia

• Acute myeloblastic leukaemia

• Chronic myeloid leukaemia

• Acute lymphoblastic leukaemia

What is the significance of cytogenetic analysis in leukaemia?

• To determine gene mutation

• To identify chromosome abnormalities

• To measure gene expression

• To assess cell morphology

What is the typical laboratory finding in a patient with chronic myeloid leukaemia (CML)?

• Leukocytosis

• Thrombocytopenia

• Anemia

• Leukopenia

What does the term 'blast phase' refer to in chronic myeloid leukaemia (CML)?

• The initial diagnosis phase

• The phase of complete remission

• The phase with >20% blasts

• The phase with 1 - 5% blasts

What is the typical presentation of acute myeloid leukaemia (AML) in a peripheral blood film?

• Presence of mature granulocytes

• Presence of myeloblasts

• Presence of lymphocytes

• Presence of erythrocytes

Which classification system is used for Acute Lymphoblastic Leukaemia by morphology?

• American Society of Hematology (ASH)

• French-American-British (FAB)

• World Health Organization (WHO)

• National Cancer Institute (NCI)

The image shows chromosomes of a patient with chronic myeloid leukaemia. What is the finding?

• t(8;21)(q22;q22)

• del(9)(q34)

• t(9;22)(q34;q11)

• del(22)(q11)

What is the primary characteristic of Chronic Lymphocytic Leukaemia (CLL)?

• High levels of hemoglobin

• Presence of blast cells

• Accumulation of mature lymphocytes

• Accumulation of immature lymphocytes