DNA Replication Concepts and Mechanisms

In eukaryotic cells, where does DNA replication primarily take place?

• Cytoplasm

• Mitochondria

• Nucleus

• Ribosomes

During which phase of the cell cycle does DNA replication occur in eukaryotic cells?

• Cell Division

• Interphase

• Mitosis

• Meiosis

What is the main role of the enzyme Helicase in DNA replication?

• To build new DNA strands.

• To initiate DNA synthesis by creating a primer.

• To separate the two strands of the DNA double helix.

• To join DNA fragments together.

What does it mean for DNA strands to be antiparallel?

• They run in the same direction, from 5' to 3'.

• They run in opposite directions, one 5' to 3' and the other 3' to 5'.

• They are parallel but do not interact with each other.

• They are composed of different types of nucleotides.

During DNA replication, why is the lagging strand synthesized in fragments (Okazaki fragments)?

• DNA polymerase can only add nucleotides to the 5' end of a growing strand.

• DNA polymerase can only add nucleotides to the 3' end of a growing strand.

• Helicase unwinds the DNA too quickly for continuous synthesis on both strands.

• Primase can only place primers at specific intervals on the lagging strand.