Skin - Lecture 10

What type of antimicrobial molecule is produced by the sebaceous glands?

• Lysozyme

• Fatty acids

• Major basic protein

• Surfactant protein A

Why does increased sebum production increase the risk of skin infection?

• It inhibits the activation of mast cells

• It inhibits the movement of neutrophils

• It inhibits epithelial cell keratinization

• Microbes in the normal microbiota overgrow

Which of the following skin defences use perforin and granzyme to kill infected cells?

• Mast cells and eosinophils

• Keratinocytes and sebocytes

• Neutrophils and macrophages

• Natural killer cells and Tc cells

Which T helper cell response is MOST important for defence against intracellular skin infections like Mycobacterium leprae?

• Th1 cells

• Th2 cells

• Th17 cells

• Th22 cells

Bee sting venom sometimes causes urticaria (hives) and anaphylaxis. What type of immune disease is this?

• Type I hypersensitivity

• Type II hypersensitivity

• Type III hypersensitivity

• Type IV hypersensitivity

Which of the following opportunistic pathogens is found in the normal skin microbiota?

• Candida albicans

• Bacteroides fragilis

• Clostridioides difficile

• Neisseria meningitidis