Pharmacology Practice Quiz

What does the onset of action describe?

• How long the drug stays in the system

• How quickly the drug is excreted

• How quickly the drug takes effect

• How the drug binds to proteins

The duration of action of a drug refers to:

• How long the drug stays on the shelf

• How long it takes to metabolize the drug

• How long the drug has a therapeutic effect

• How long it takes for the drug to reach the liver

The purpose of a maintenance dose is to:

• Increase the onset of action

• Achieve a peak drug concentration

• Maintain a desired drug level in the blood

• Reduce the risk of side effects

A loading dose is used to:

• Decrease metabolism of a drug

• Quickly achieve therapeutic levels

• Slow the drug's excretion

• Increase enzyme activity

Peak level refers to:

• The lowest concentration of drug in the blood

• The first dose given

• The highest concentration of drug in the blood

• The time when the drug is first absorbed

Trough level is defined as:

• The amount of drug needed for a loading dose

• The lowest concentration of drug in the blood

• The amount of drug excreted

• The most common dose used

What is steady state?

• When drug absorption stops

• When metabolism exceeds excretion

• When drug intake equals drug elimination

• When side effects are reduced

Which of the following affects drug absorption?

• Route of administration

• Patient's age

• Metabolic rate

• All of the above

The blood-brain barrier primarily:

• Increases drug absorption

• Prevents drugs from being excreted

• Limits drug entry into the brain

• Speeds up metabolism

The first-pass effect refers to drug metabolism that occurs in the:

• Kidneys

• Brain

• Liver

• Lungs