Abrams Chapter 26

What is the primary goal of antihypertensive therapy?

• Cure hypertension

• Prevent end-organ damage

• Increase cardiac output

• Reduce heart rate

Which class of drugs is considered first-line for managing hypertension?

• Beta blockers

• ACE inhibitors

• Calcium channel blockers

• Thiazide diuretics

ACE inhibitors lower blood pressure by:

• Blocking calcium channels

• Increasing aldosterone

• Inhibiting angiotensin-converting enzyme

• Stimulating beta receptors

A common adverse effect of ACE inhibitors is:

• Diarrhea

• Dry cough

• Bradycardia

• Muscle cramps

5. The lab value that should be monitored in patients taking ACE inhibitors is:

• Potassium

• Calcium

• Sodium

• Glucose

What is the mechanism of action of angiotensin II receptor blockers (ARBs)?

• Promote sodium retention

• Inhibit renin

• Block angiotensin II receptors

• Decrease aldosterone secretion

Which of the following is a contraindication for beta-blocker use?

• A. Atrial fibrillation

• B. Chronic heart failure

• C. Asthma

• D. Hypertension

What is the primary action of calcium channel blockers?

• Decrease heart contractility and dilate arteries

• Increase peripheral resistance

• Stimulate cardiac conduction

• Inhibit aldosterone

Which adverse effect is most associated with calcium channel blockers?

• Constipation

• Hypokalemia

• Sedation

• Dry mouth

Beta blockers primarily lower blood pressure by:

• Increasing renal blood flow

• Blocking beta-adrenergic receptors

• Stimulating alpha receptors

• Enhancing calcium reuptake