Abrams Chapter 28

What is the primary goal of drug therapy for coronary heart disease (CHD)?

• Increase heart rate

• Reduce myocardial oxygen demand and prevent complications

• Enhance digestion

• Stimulate clot formation

Nitroglycerin relieves angina by:

• Increasing preload

• Dilating coronary arteries

• Blocking beta receptors

• Increasing afterload

Which of the following is a common side effect of nitrates?

• Bradycardia

• Headache

• Dry mouth

• Edema

What is the proper method to administer sublingual nitroglycerin during chest pain?

• Swallow it with water

• Chew the tablet

• Place under the tongue and wait for absorption

• Inject into the muscle

A patient should do which of the following if chest pain is not relieved after one dose of nitroglycerin?

• Call emergency services immediately.

• Take another medication without consulting a doctor.

• Ignore the pain and rest.

• Wait an hour before taking further action.

Beta blockers help manage CHD by:

• Increasing cardiac contractility

• Blocking sympathetic stimulation to reduce heart rate and oxygen demand

• Enhancing digestion

• Promoting diuresis

Atenolol and metoprolol are examples of:

• Calcium channel blockers

• Beta blockers

• ACE inhibitors

• Diuretics

Which class of drugs can be used to treat variant (Prinzmetal's) angina?

• Nitrates

• Calcium channel blockers

• Beta blockers

• Statins

What is a serious contraindication to nitrate therapy?

• Asthma

• Hypotension

• Diabetes

• Hyperlipidemia

Which medication should be avoided with nitrates due to risk of severe hypotension?

• Acetaminophen

• Sildenafil

• Metformin

• Simvastatin