BIOL1306 Chapter 14 - O'Neal

Match the following

• Miescher

• Discovered phosphate-rich material in nuclei.

• Okazaki fragments

• Used X-ray diffraction to uncover DNA’s shape.

• Telomerase

• The directionality of DNA strands.

• Franklin

• Enzyme that extends telomeres in germ cells.

• Antiparallel

• Short lagging strand segments synthesized discontinuously.

DNA replication in E. coli is:

• Slow and linear

• Circular and rapid

• Bidirectional but slow

• Unidirectional and complex

The DNA helix is ___ nm in diameter and makes one complete turn every ___ base pairs.

• 1 nm; 20

• 3.4 nm; 10

• 2 nm; 10

• 5 nm; 100

Which enzyme unwinds the DNA helix?

• Primase

• Ligase

• Helicase

• Polymerase I

What does DNA Polymerase III require to begin synthesis?

• dNTPs

• Telomere

• RNA primer

• DNA ligase

The leading strand is synthesized:

• In fragments

• From 3' to 5'

• Continuously in the 5' → 3' direction

• Without a primer

DNA strands are described as ____________ because they run in opposite directions.

• _____-______ ______ _______ are proteins that hold DNA strands apart during replication.

• The enzyme ____ ________ joins Okazaki fragments on the lagging strand.

_______ _____ is the process of proofreading and correcting mismatched base pairs.