DDD SAS 3 ACTIVITY

What’s the first step in drug discovery?

• Target Optimization

• Target Identification

• Assay Development

• Dose Response Curve

A “HIT” in drug discovery is like...

• A failed experiment

• An actual drug

• A compound that shows activity

• A type of side effect

Which of these is NOT a source of drug leads?

• Natural products

• Marine organisms

• Spoiled food

• Soil microbes

What does HTS stand for?

• High Tea Session

• Highly Toxic Substance

• High Throughput Screening

• Humble Target Strategy

Which animal-inspired substance led to ACE inhibitors?

• Frog venom

• Snake venom

• Pig sweat

• Dolphin tears

Goal of lead optimization:

• To identify new diseases

• To improve drug selectivity and safety

• To test drugs on humans immediately

• To increase manufacturing cost

Generic name of the drug studied for heart conditions but later found effective for treating erectile dysfunction. (Write in ALL CAPS)