Adverse Drug Reactions Quiz

Which of the following best defines an Adverse Drug Reaction (ADR)?

• Intentional drug misuse

• Harmful reaction at normal dose

• Drug overdose

• Medication error

Which organization defines ADR as a "noxious and unintended response at normal doses"?

• FDA

• WHO

• CDC

• ICH

Which of the following is NOT considered an ADR?

• Anaphylaxis due to penicillin

• Headache from aspirin at normal dose

• Liver damage due to paracetamol overdose

• Rash after sulfa drug administration

ADR differs from a side effect because:

• Side effects are not dose-dependent

• ADRs are always mild

• Side effects are known and predictable

• ADRs occur only in children

Which is a Type B (bizarre) ADR?

• Diarrhea with antibiotics

• Hypoglycemia with insulin

• Anaphylaxis with penicillin

• Drowsiness with antihistamines

Type A ADRs are typically:

• Unpredictable

• Immunologic

• Dose-dependent

• Genetic

Which of the following is a delayed ADR?

• Rash within minutes

• Tardive dyskinesia with antipsychotics

• Cough due to ACE inhibitors

• Nausea with metformin

Which system is most commonly involved in ADRs?

• Respiratory

• Gastrointestinal

• Nervous

• Cardiovascular

Who is most at risk for ADRs?

• Middle-aged athletes

• Children

• Young adults

• Elderly on polypharmacy

Which is an example of a dose-independent ADR?

• Nausea with metronidazole

• Hepatotoxicity with isoniazid

• Anaphylaxis to penicillin

• Sedation with diazepam