Targeted Chemotherapy Quiz (Multiple Choice)

What is the MOA of imatinib?

• EGFR inhibitor

• BCR-ABL tyrosine kinase inhibitor

• PD-1 checkpoint inhibitor

• CD20 monoclonal antibody

What is the most common target of rituximab?

• HER2

• CD30

• CD20

• VEGF

Which of the following is a HER2/neu monoclonal antibody?

• Cetuximab

• Bevacizumab

• Trastuzumab

• Blinatumomab

Bevacizumab inhibits which molecule?

• EGFR

• VEGF

• BCR-ABL

Cetuximab targets which receptor?

• VEGF

• PD-1

• EGFR

• HER2

Brentuximab vedotin targets which antigen?

• CD20

• CD19

• CD30

• HER2

Nivolumab is an example of what type of drug?

• Monoclonal antibody

• Immune checkpoint inhibitor

• TKI

• Antiangiogenic

Tisagenlecleucel is a form of what therapy?

• BiTE

• CAR T-cell therapy

• Checkpoint inhibitor

• Antibody-drug conjugate

Blinatumomab links which two targets?

• CD20 and CD30

• CD3 and CD19

• PD-1 and PD-L1

• EGFR and VEGF

Dasatinib inhibits which two kinases?

• EGFR and HER2

• BCR-ABL and SRC

• PD-1 and VEGF

• ALK and ROS1