Chapter 2 Fall 2025

In a healthy adult, the average myeloid-to-erythroid (M:E) ratio in bone marrow is approximately:

• 1:3

• 4:1

• 1:4

• 6:1

Tags

NGSS.HS-LS1-4

Which organs are the primary sites for extramedullary hematopoiesis?

• Heart and thymus

• Kidney and thyroid

• Liver and spleen

• Lymph nodes and pancreas

A rapid and reliable test for evaluating bone marrow response to anemia is:

• Hemoglobin concentration

• Hematocrit measurement

• Reticulocyte count

• Mean corpuscular volume

Which of the following is not a hematopoietic role of the spleen?

• Producing antibodies that enhance phagocytosis

• Storing platelets and certain white blood cells

• Filtering damaged or aged erythrocytes

• Producing white blood cells when needed

At 4–5 months of fetal development, the main site of hematopoiesis is the:

• Liver

• Yolk sac

• Axial skeleton

• Distal long bones

A patient’s CBC reveals: RBC = 4.01 × 10¹²/L, Hgb = 12.5 g/dL, Hct = 37.2%. Which RBC index values are correct?

• MCV ≈ 92.8 fL, MCH ≈ 31.2 pg, MCHC ≈ 33.6%

• MCV ≈ 92.8 fL, MCH ≈ 33.6 pg, MCHC ≈ 31.2%

• MCV ≈ 107.8 fL, MCH ≈ 32.1 pg, MCHC ≈ 33.6%

• MCV ≈ 132.2 fL, MCH ≈ 32.1 pg, MCHC ≈ 33.5%

For adult bone marrow aspiration and biopsy, the recommended site is:

• Sternum

• Iliac crest

• Tibia

• Vertebra

A patient has a hemoglobin of 12.3 g/dL, with normocytic, normochromic erythrocytes. Which hematocrit would be most consistent?

• 34%

• 37%

• 40%

• 43%

When examining bone marrow with a Wright stain, all these cells are seen except:

• Sideroblasts (iron-containing precursors) without special staining

• Erythroid precursor cells

• Myeloid precursor cells

• Mature granulocytes

Erythropoietin, the hormone that stimulates red blood cell production, is primarily secreted by the:

• Kidneys

• Liver

• Spleen

• Bone marrow

Tags

NGSS.HS-LS1-3