Biso + Telmi PK & POA MCQs

Bisoprolol is classified as:

• Non-selective beta blocker

• Highly selective Beta-1 adrenoceptor antagonist

• Alpha blocker

• Calcium channel blocker

Bisoprolol's selectivity for beta-1 receptor is:

• 5-fold higher than beta-2

• 10-fold higher than beta-2

• 19-fold higher than beta-2

• 25-fold higher than beta-2

Which generation of beta blocker is Bisoprolol?

• First-generation

• Second-generation

• Third-generation

• Fourth-generation

Bisoprolol has been available worldwide for:

• 10 years

• 20 years

• 35 Years

• 40 years

Bisoprolol's mechanism in hypertension involves blocking beta1 receptors in:

• Heart only

• Juxtaglomerular cells

• Lungs

• Kidneys only

The duration of action of Bisoprolol is:

• 8 hours

• 12 hours

• 24 hours

• 48 hours

Bisoprolol's intrinsic sympathomimetic activity is:

• High

• Moderate

• Low

• No intrinsic sympathomimetic activity

What percentage of Bisoprolol undergoes renal elimination unchanged?

• 25%

• 50%

• 75%

• 100%

What percentage of Bisoprolol undergoes hepatic metabolism?

• 25%

• 50%

• 75%

• 100%

Dose adjustment of Bisoprolol is necessary in:

• Mild to moderate liver impairment

• Mild to moderate kidney impairment

• Both mild to moderate liver and kidney impairment

• No dose adjustment necessary in mild to moderate impairment