A 45-year-old man with inoperable pheochromocytoma is started on an irreversible α-blocker that also has a rare use in scorpion sting–induced hypertension.

• Phentolamine

• Prazosin

• Phenoxybenzamine

• Yohimbine

A 60-year-old female with chronic hiccups is prescribed a dopamine antagonist that also has rare FDA approval for severe nausea.

• Haloperidol

• Chlorpromazine

• Domperidone

• Risperidone

A patient with cyanide poisoning is treated with a drug also used as an antihypertensive. The drug releases cyanide-binding sulfur groups.

• Sodium nitroprusside

• Sodium thiosulfate

• Hydralazine

• Labetalol

A patient with Wilson’s disease who cannot tolerate penicillamine is given a chelator originally approved for iron overload.

• Deferoxamine

• Deferiprone

• Deferasirox

• EDTA

A patient with severe methotrexate toxicity is treated with a drug originally developed for pesticide exposure.

• Methylene blue

• Glucarpidase

• Atropine

• Pralidoxime

A 19-year-old woman with severe acne is given an antibiotic also used in visceral leishmaniasis and Pneumocystis jirovecii pneumonia.

• Minocycline

• Dapsone

• Amphotericin B

• Pentamidine

During surgery, a patient with myasthenia gravis is given a short-acting cholinesterase inhibitor for diagnosis and to avoid prolonged paralysis.

• Neostigmine

• Pyridostigmine

• Edrophonium

• Rivastigmine

A child with infantile spasms is treated with a drug that irreversibly inhibits GABA transaminase.

• Vigabatrin

• Tiagabine

• Valproate

• Gabapentin

A patient with carcinoid syndrome and diarrhea is treated with a drug also used in esophageal variceal bleeding prophylaxis.

• Octreotide

• Lanreotide

• Vasopressin

• Terlipressin

A 40-year-old alcoholic is prescribed a drug originally developed as an anthelmintic, now used to maintain abstinence.

• Disulfiram

• Acamprosate

• Naltrexone

• Baclofen