NSAIDs and Opioids Quiz

What is a TRUE characteristic of conventional NSAIDs?

• They specifically inhibit only COX-2

• They inhibit both COX-1 and COX-2, causing potential gastrointestinal effects

• They do not affect platelet function

• They are safe in patients with active gastric ulcers

For a patient with chronic gastritis who needs an NSAID, which is the BEST option?

• Acetylsalicylic acid

• Naproxen

• Paracetamol (Acetaminophen)

• Indomethacin

Which of these actions is NOT a property of NSAIDs?

• Anti-inflammatory effect

• Antipyretic action

• Sedative and hypnotic properties

• Analgesic capacity

A 64-year-old man with back pain, resolved gastric ulcer, and cardiovascular risk does not respond to paracetamol. What is the MOST appropriate treatment?

• Acetylsalicylic acid

• Naproxen alone

• Naproxen + Omeprazole

• Diclofenac

The three main therapeutic effects of NSAIDs related to COX inhibition are:

• Anti-platelet, analgesic, and antipyretic

• Anti-inflammatory, analgesic, and antipyretic

• Anti-inflammatory, analgesic, and anti-platelet

• Antipyretic, muscle relaxant, and anti-inflammatory

Which statement about NSAIDs is INCORRECT?

• They are ineffective in acute inflammation

• They reduce fever by central inhibition of prostaglandins

• Their antiplatelet potency varies among different NSAIDs

• They all inhibit COX-1 to the same degree

Which NSAID irreversibly inhibits COX-1 and COX-2 and has an antiplatelet effect at low doses?

• Ibuprofen

• Diclofenac

• Paracetamol

• Acetylsalicylic acid (Aspirin)

The main mechanism of action of NSAIDs is:

• Inhibition of histamine release

• Blockade of cyclooxygenase (COX)

• Stimulation of prostaglandin synthesis

• Activation of opioid receptors

An asthmatic patient with low back pain. Which analgesic is the SAFEST?

• Ibuprofen

• Acetylsalicylic acid

• Paracetamol (Acetaminophen)

• Naproxen

The anti-inflammatory effect of corticosteroids is mainly due to:

• Inhibition of COX-1 and COX-2

• Inhibition of phospholipase A2

• Blockade of histamine receptors

• Inhibition of serotonin reuptake