Week 1 Quiz

A 25-year-old man presents with fatigue and jaundice. His hepatitis B serology shows: HBsAg positive, anti-HBc IgM positive, anti-HBs negative. What is the most likely interpretation?

Which investigation is most specific for diagnosing coeliac disease in a patient with chronic diarrhoea and weight loss?

A 32-year-old woman with a history of Crohn’s disease presents with abdominal pain and diarrhoea. Which medication is most appropriate for inducing remission in moderate to severe Crohn’s disease?

Which of the following is a distinguishing histological feature of ulcerative colitis compared to Crohn’s disease?

A 45-year-old man with a history of alcohol misuse presents with ascites and spider naevi. Which investigation is most useful to confirm the diagnosis of cirrhosis?

Which of the following is the first-line management for a patient newly diagnosed with coeliac disease?

Which serological marker profile best indicates immunity to hepatitis B due to vaccination?

A 60-year-old obese woman with type 2 diabetes is found to have elevated liver enzymes and hepatomegaly. Which is the most likely underlying pathophysiological process in non-alcoholic fatty liver disease (NAFLD)?

Which of the following medications is commonly used for maintenance of remission in ulcerative colitis?

A 28-year-old man with Crohn’s disease develops perianal fistulae. Which medication is most appropriate for treating complex perianal Crohn’s disease?