Trypanosoma cruzi Life Cycle and Transmission

The video from Medicofem YouTube channel explains the life cycle of Trypanosoma Cruzi, a parasite that requires two hosts: humans and reduviate bugs, also known as kissing bugs. It details various transmission methods, including blood transfusion and vertical transmission. The video describes how the parasite invades host cells, forming parasitophorus vacuoles and transforming into amastigotes. These amastigotes multiply and form pseudocysts, eventually releasing trypomastigotes into the bloodstream. The trypomastigotes exist in two forms: slender, highly motile forms that invade organs, and broader, less motile forms that persist in the blood. The video concludes with a call to action for viewers to share and subscribe.

What are the two hosts in the life cycle of Trypanosoma cruzi?

• Human and sandfly

• Human and tsetse fly

• Human and reduviate bugs

• Human and mosquito

Which of the following is NOT a transmission method for Trypanosoma cruzi?

• Vertical transmission from mother to child

• Blood transfusion

• Airborne transmission

• Organ transplantation

After entering the blood, which cells does Trypanosoma cruzi invade first?

• Kidney cells

• Liver cells

• Macrophages

• Red blood cells

What is formed inside macrophages after Trypanosoma cruzi invades them?

• Pseudocyst

• Parasitophorous vacuole

• Cysticercus

• Sporozoite

What transformation occurs inside the parasitophorous vacuole?

• Formation of cysticercus

• Formation of sporozoite

• Transformation into a trophozoite

• Transformation into a mastigote form

How does Trypanosoma cruzi multiply within the host cells?

• By conjugation

• By sporulation

• By budding

• By binary fission

What is the term for the massive growth formed by multiplying amastigotes?

• Trophozoite

• Sporozoite

• Pseudocyst

• Cysticercus

What are the two types of trypomastigotes liberated into the blood?

• Slender highly motile and broader less motile

• Slender less motile and broader highly motile

• Slender motile and broader non-motile

• Slender non-motile and broader motile

Which type of trypomastigote is invasive and migrates to many organs?

• Broader highly motile

• Slender highly motile

• Slender less motile

• Broader less motile

What happens to the broader less motile trypomastigotes?

• They invade organs

• They persist in blood and are taken up by insect vectors

• They transform into cysts

• They multiply by binary fission