Serine, Glycine Biosynthesis

The video tutorial explains the biosynthesis of serine, glycine, and cysteine from the glycolysis intermediate 3-phosphoglycerate. It details the enzymatic steps involved in converting 3-phosphoglycerate to serine and then to glycine, highlighting the role of methylene tetrahydrofolate in nucleotide and SAM synthesis. The tutorial also discusses the energy dynamics of these pathways, noting the unusual generation of NADH due to the high energy of 3-phosphoglycerate.

Which glycolysis intermediate is used in the synthesis of serine, glycine, and cysteine?

• Fructose-6-phosphate

• Glucose-6-phosphate

• 3-phosphoglycerate

• Pyruvate

What enzyme is responsible for converting serine to glycine?

• Phosphoglycerate dehydrogenase

• Serine hydroxymethyl transferase

• Phosphoserine aminotransferase

• Phosphoserine phosphatase

Methylene tetrahydrofolate is crucial for the synthesis of which DNA component?

• Guanine

• Cytosine

• Adenine

• Thymine

What is the role of methylene tetrahydrofolate in methionine synthesis?

• It acts as a phosphate donor

• It provides an amino group

• It acts as a methyl group donor

• It serves as an energy source

What is unusual about the biosynthetic pathway of serine, glycine, and cysteine?

• It consumes ATP

• It generates NADH

• It requires oxygen

• It produces carbon dioxide