Hemophilia A vs Hemophilia B | Genetics, Symptoms and Treatment

The video tutorial explains hemophilia A and B, both hereditary disorders affecting blood clotting due to deficiencies in factors 8 and 9, respectively. It covers symptoms like delayed bleeding and hemarthrosis, diagnostic lab tests showing increased PTT, and treatment options including desmopressin and factor concentrates. The coagulation cascade is detailed, highlighting the role of thrombin and fibrin in clot formation. The tutorial concludes with a comparison of the two types, emphasizing their similarities and differences.

What is the primary cause of hemophilia A?

• Vitamin K deficiency

• Platelet dysfunction

• Factor 8 deficiency

• Factor 9 deficiency

Which of the following is a common presentation of hemophilia?

• Delayed bleeding after injury

• Immediate bleeding after injury

• Frequent nosebleeds

• Excessive bruising

What laboratory finding is typically increased in hemophilia A?

• Platelet count

• PTT

• INR

• PT

What is the main treatment for severe hemophilia A?

• Vitamin K

• Factor 8 concentrate

• Desmopressin

• Platelet transfusion

Hemophilia B is primarily caused by a deficiency in which factor?

• Factor 13

• Factor 11

• Factor 9

• Factor 8

Which treatment is specific to hemophilia B?

• Factor 9 concentrate

• Factor 8 concentrate

• Desmopressin

• Vitamin K

What is the role of factor 8 in the coagulation cascade?

• Activates factor 10

• Cleaves prothrombin to thrombin

• Converts fibrinogen to fibrin

• Activates factor 9