Phosphoglucomutase: Linking Glycogen to Glycolysis

The video tutorial provides a comprehensive overview of glycogenolysis, explaining how glycogen is broken down into glucose 1 phosphate by glycogen phosphorylase. It highlights the need to convert glucose 1 phosphate to glucose 6 phosphate using phosphoglucomutase for glycolysis. The tutorial also touches on the metabolic pathways leading to pyruvate and the TCA cycle. Additionally, it introduces glycogenesis, emphasizing the reversible nature of phosphoglucomutase and the regulation of these processes.

What is the main enzyme responsible for breaking down glycogen into glucose 1 phosphate?

• Glycogen synthase

• Glycogen phosphorylase

• Hexokinase

• Phosphoglucomutase

Why is glucose 1 phosphate not directly useful in glycolysis?

• It is too large to enter the glycolysis pathway

• It lacks a phosphate group

• It is not a sugar molecule

• Glycolysis requires glucose 6 phosphate

Which enzyme converts glucose 1 phosphate to glucose 6 phosphate?

• Phosphoglucomutase

• Hexokinase

• Glycogen phosphorylase

• Aldolase

What is the ultimate fate of glucose 6 phosphate in the metabolic pathway?

• It is stored as glycogen

• It is converted into pyruvate

• It is excreted from the cell

• It is used to synthesize proteins

In glycogenesis, what is the role of phosphoglucomutase?

• It converts glucose 6 phosphate to glucose 1 phosphate

• It breaks down glycogen into glucose

• It removes phosphate groups from glucose

• It adds phosphate groups to glucose