What organelles are primarily involved in the maturation of insulin?
The Mechanism of Insulin Biosynthesis by Pancreatic β-cells

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Science, Biology, Chemistry
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7 questions
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1.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Mitochondria and Lysosomes
Rough ER and Golgi Apparatus
Nucleus and Ribosomes
Smooth ER and Peroxisomes
2.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the initial form of insulin produced by the ribosome?
Mature Insulin
Proinsulin
Preproinsulin
C-peptide
3.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which process is necessary for the formation of disulfide bridges in insulin?
Reduction
Oxidation
Hydrolysis
Phosphorylation
4.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the role of the signal peptide in insulin processing?
It is part of the mature insulin structure.
It signals the protein to remain in the cytosol.
It directs the protein to the rough ER lumen.
It helps in the formation of disulfide bridges.
5.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
Which enzyme is responsible for cleaving the signal peptide?
Ribosome
Prohormone Convertase
Carboxypeptidase E
SEC 11
6.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What is the final step in the maturation of insulin?
Cleavage of the signal peptide
Translation of mRNA
Formation of disulfide bridges
Removal of C-terminal amino acids
7.
MULTIPLE CHOICE QUESTION
30 sec • 1 pt
What triggers the release of insulin into the blood?
The presence of glucagon
The amount of ATP in the cell
The concentration of sodium ions
The level of intracellular calcium
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