Vitamin B5 [Pantothenic Acid] | Salvage, CoA Biosynthesis, & Other Facts

The video explains the importance of vitamin B5, also known as pantothenic acid, which is salvaged from the diet and gut bacteria. It highlights the top dietary sources and the chemical structure of vitamin B5, emphasizing its conversion to coenzyme A. The video details the metabolic pathways involving coenzyme A and its critical role in cellular functions, including fatty acid metabolism and the Krebs cycle. It also discusses the impact of vitamin B5 on neuronal health and its potential link to Alzheimer's disease, concluding with health recommendations for adequate vitamin B5 intake.

What is the primary reason humans cannot synthesize vitamin B5 from scratch?

• Lack of necessary enzymes

• Absence of gut bacteria

• Insufficient dietary intake

• Inability to absorb nutrients

Which of the following is NOT a top food source of vitamin B5?

• Broccoli

• Lean chicken

• Shiitake mushrooms

• Salmon

What happens to coenzyme A in the intestines before it can be absorbed?

• It is directly absorbed

• It is excreted

• It is converted to pantothenic acid

• It is stored for later use

Which enzyme is responsible for the initial conversion of coenzyme A to dephospho coenzyme A?

• Choline acetyltransferase

• Alkaline phosphatase

• Pantothenate kinase

• Ecto nucleotide pyrophosphatase

What is the final product of the conversion of coenzyme A in the intestines?

• Pantothenic acid

• Adenosine monophosphate

• Sphingomyelin

• Cysteamine

In which organ is pantothenic acid primarily converted back into coenzyme A?

• Heart

• Brain

• Liver

• Kidneys

Which enzyme initiates the conversion of pantothenic acid to coenzyme A in cells?

• Coenzyme A synthase

• Pantothenate kinase

• Alkaline phosphatase

• Choline acetyltransferase

What is a key role of coenzyme A in neurons?

• Synthesis of sphingomyelin

• Production of acetylcholine

• Formation of beta amyloid plaques

• Regulation of blood flow

How does vitamin B5 deficiency potentially relate to Alzheimer's disease?

• It causes beta amyloid plaques

• It enhances memory retention

• It leads to neurodegeneration and dementia

• It increases blood pressure

What is the significance of vitamin B5 in brain health?

• It is a major component of myelin

• It is well tolerated in high doses

• It directly forms neurotransmitters

• It prevents all forms of dementia