Direct Fibrinolysis: The Plasmin Pathway

The video explains the process of fibrinolysis, focusing on the plasmin pathway. It describes how plasminogen is activated into plasmin, which then degrades fibrin and fibrinogen. The video also covers the formation of fibrinolysis products like D dimers and discusses the regulation of coagulation to maintain cardiovascular health.

What is the primary function of the protein C pathway?

• To directly degrade fibrin

• To prevent new fibrin formation

• To activate plasminogen

• To form blood clots

Which of the following is a plasminogen activator?

• Thrombin

• Fibrinogen

• Urokinase

• Collagen

What is the role of plasmin in fibrinolysis?

• It forms fibrin clots

• It inhibits clotting factors

• It hydrolyzes fibrin

• It activates plasminogen

What are D dimers?

• Inactive forms of plasmin

• Products of fibrin formation

• Clotting factors

• Products of fibrin degradation

Which fragment is formed after plasmin acts on non-crosslinked fibrin?

• Fragment X

• Fragment Y

• D dimers

• E domain

Why is fibrinolysis important for cardiovascular health?

• It forms new blood vessels

• It prevents blood clot formation

• It ensures blood clots are degraded

• It activates clotting factors

What happens to fibrinolysis products eventually?

• They remain in the bloodstream

• They are recycled to amino acids

• They are converted back to fibrin

• They form new clots