Anti-platelet Medications + Mechanisms of Action

The video tutorial explains the role of antiplatelet drugs in preventing blood clots and strokes. It covers the mechanisms of action of aspirin, which inhibits Cox-1 to prevent thromboxane A2 formation, and Clopidogrel, which blocks the P2Y12 receptor to prevent ADP-induced platelet activation. The tutorial also discusses glycoprotein receptors involved in platelet adhesion and their inhibitors. Additionally, it highlights the importance of pharmacogenomics in determining the effectiveness of Clopidogrel due to genetic polymorphisms.

Describe the mechanism by which clopidogrel inhibits platelet activation.

What is the role of glycoprotein receptors in platelet adhesion?

Discuss the risks associated with the use of antiplatelet drugs.