Folate and Tetrahydrofolate Metabolism

Folate and Tetrahydrofolate Metabolism

Assessment

Interactive Video

Science, Chemistry

University

Hard

Created by

Quizizz Content

FREE Resource

The video tutorial explains the role of tetrahydrofolate and its derivatives in biosynthetic reactions. It covers how humans obtain folate from the diet and convert it into tetrahydrofolate in the liver. The tutorial details the conversion of tetrahydrofolate into various derivatives, highlighting the importance of methylenetetrahydrofolate in DNA synthesis and methyltetrahydrofolate in the SAM cycle. The significance of folate intake, especially during pregnancy, is emphasized due to its role in preventing neural tube defects.

Read more

10 questions

Show all answers

1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the primary role of tetrahydrofolate derivatives in biosynthetic reactions?

Delivering two carbons at a time

Delivering one carbon at a time

Delivering oxygen atoms

Delivering nitrogen atoms

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

How do humans obtain tetrahydrofolate?

Through biosynthesis in the liver

Through dietary intake as folate or folic acid

Through exposure to sunlight

Through inhalation

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme is responsible for converting folic acid to tetrahydrofolate?

Serine hydroxymethyltransferase

Cyclohydrolase

Methionine synthase

Dihydrofolate reductase

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the role of N10-formyl tetrahydrofolate in nucleic acid biosynthesis?

It donates a formyl group

It donates a methyl group

It donates a hydroxyl group

It donates a phosphate group

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which enzyme converts N5,N10-methenyl tetrahydrofolate into N5-formimino tetrahydrofolate?

Serine hydroxymethyltransferase

N5,N10-methylenetetrahydrofolate reductase

Cyclohydrolase

Methionine synthase

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the significance of N5,N10-methylene tetrahydrofolate in DNA synthesis?

It is used to synthesize cytosine

It is used to synthesize guanine

It is used to synthesize thymine

It is used to synthesize adenine

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which coenzyme is necessary for the generation of S-adenosylmethionine?

N10-formyl tetrahydrofolate

N5,N10-methylenetetrahydrofolate

N5-formimino tetrahydrofolate

N5-methyltetrahydrofolate

Create a free account and access millions of resources

Create resources
Host any resource
Get auto-graded reports
or continue with
Microsoft
Apple
Others
By signing up, you agree to our Terms of Service & Privacy Policy
Already have an account?