Whole-Body Cholesterol Transport [Part 2/2] | LDL & HDL

The video explains the roles of different lipoproteins in cholesterol transport. It covers the functions of chylomicrons, VLDL, LDL, and HDL, detailing how LDL delivers cholesterol to peripheral tissues and how HDL performs reverse cholesterol transport. The regulation of LDL levels and cholesterol synthesis by the liver is also discussed, highlighting the feedback mechanisms involved.

What is the primary function of chylomicrons?

• Delivery of free fatty acids to peripheral tissues

• Transport of cholesterol to the liver

• Conversion of LDL to HDL

• Synthesis of triglycerides

What is the role of hepatic lipase in cholesterol transport?

• Synthesizes cholesterol

• Converts LDL to HDL

• Converts IDL to LDL

• Breaks down triglycerides in chylomicrons

How does LDL deliver cholesterol to peripheral tissues?

• By binding to HDL

• By direct diffusion through the cell membrane

• By converting cholesterol to triglycerides

• Through receptor-mediated endocytosis

Which of the following is a major site of cholesterol processing in cells?

• Nucleus

• Mitochondria

• Smooth endoplasmic reticulum

• Golgi apparatus

What happens to LDL if it is not internalized by peripheral cells?

• It returns to the liver

• It is excreted from the body

• It converts to HDL

• It remains in the bloodstream indefinitely

What triggers the liver to reduce cholesterol synthesis?

• High levels of LDL returning to the liver

• Low levels of LDL returning to the liver

• Low levels of triglycerides in the blood

• High levels of HDL in the blood

Which organ is primarily responsible for the synthesis of cholesterol in the body?

• Liver

• Pancreas

• Heart

• Kidneys

What is the primary function of HDL in cholesterol transport?

• Conversion of LDL to VLDL

• Synthesis of cholesterol in the liver

• Reverse cholesterol transport

• Transport of triglycerides to adipose tissue

What is the significance of the high protein content in HDL?

• It makes HDL more stable in the bloodstream

• It enables HDL to pick up excess lipids

• It prevents HDL from being internalized by cells

• It allows HDL to transport more cholesterol

What is the precursor for steroid hormones in the adrenal glands?

• Phospholipids

• Triglycerides

• Cholesterol

• Proteins