Organometallic Reactions Part 5: Nucleophilic/Electrophilic Attack on Ligands

The video tutorial explores organometallic reactions, focusing on changes in metal-ligand bonds. It covers nucleophilic and electrophilic attacks on ligands, detailing how these reactions affect oxidation states and ligand structures. Examples include reactions with carbonyls, isonitriles, and alkyl ligands, demonstrating the synthetic utility of these transformations.

What happens to the oxidation state of the metal when a nucleophile attacks a carbonyl ligand?

• It increases by 1

• It decreases by 1

• It remains the same

• It doubles

Which of the following is a common nucleophile in reactions with carbine metal complexes?

• Phosphine

• Hydroxide

• Amine

• Carbanion

In an organometallic SN2-like reaction, what is attacked?

• A nitrogen atom

• An oxygen atom

• A metal atom

• A carbon atom

What is the result of an electrophilic attack on a metal-ligand pi bond?

• A decrease in the oxidation state

• An increase in the oxidation state

• A double bond formation

• No change in the oxidation state

Which ligand is involved in the electrophilic attack example with a tritle cation?

• Alkoxide

• Carbonyl

• Benzyl

• Isonitrile

What is the role of methyllithium in the manganese complex reaction?

• Inhibitor

• Catalyst

• Nucleophile

• Electrophile

In the reaction with lithium phenoxide, what is the likely site of attack?

• Alkylene carbon

• Carbonyl carbon

• Gamma carbon

• Beta carbon