Lipid Biosynthesis | Fatty Acid Biosynthesis 2: Acetyl-CoA Carboxylase

The video explains the process of fatty acid synthesis, focusing on how acetyl CoA is converted into malonyl CoA through the enzyme acetyl CoA carboxylase. It details the bifunctional nature of the enzyme, involving biotin carboxylase and transcarboxylase activities. The video also introduces fatty acid synthase, which uses malonyl CoA to synthesize fatty acids, adding two carbons at a time up to a maximum of 16 carbons. Future videos will cover the regulation of fatty acid synthesis.

What is the initial molecule transported into the cytoplasm for fatty acid synthesis?

• NADPH

• Malonyl CoA

• Citrate

• Acetyl CoA

What is the primary function of acetyl CoA carboxylase?

• To convert citrate into acetyl CoA

• To carboxylate acetyl CoA into malonyl CoA

• To synthesize fatty acids directly

• To transport acetyl CoA into the mitochondria

Which part of acetyl CoA carboxylase is responsible for carboxylating biotin?

• Acetyl CoA binding site

• Biotin carboxylase

• Malonyl CoA synthase

• Transcarboxylase

What is the maximum number of carbons in fatty acids synthesized by fatty acid synthase?

• 16

• 20

• 14

• 18

How is acetyl CoA carboxylase regulated in some organisms?

• Only allosterically

• Only transcriptionally

• Both allosterically and transcriptionally

• Not regulated