TED: How CRISPR lets us edit our DNA | Jennifer Doudna

The video discusses the CRISPR-Cas9 technology, co-invented by Jennifer Doudna and Emmanuelle Charpentier, which allows precise genome editing. Originating from bacterial immune systems, CRISPR-Cas9 can modify DNA in various organisms, offering potential cures for genetic diseases. However, its use raises ethical concerns, especially regarding human genome editing. The video calls for a global discussion on the responsible use of CRISPR, highlighting both its therapeutic potential and the risks of genetic enhancement.

What was the original purpose of the research that led to the development of CRISPR technology?

• To create genetically modified organisms

• To cure genetic diseases

• To understand how bacteria fight viral infections

• To develop new antibiotics

What role does the Cas9 protein play in the CRISPR system?

• It replicates viral DNA

• It degrades RNA

• It cuts and degrades viral DNA

• It synthesizes new DNA

How does the CRISPR technology compare to older genome engineering technologies?

• It requires more manual intervention

• It is simpler and more efficient

• It is more complex and less efficient

• It is less precise

What is one of the first potential applications of CRISPR technology in medicine?

• Treating skin diseases

• Improving vision

• Correcting blood-related genetic disorders

• Enhancing muscle growth

What ethical concern is associated with the use of CRISPR technology in human embryos?

• It could lead to the extinction of certain species

• It might cause irreversible environmental damage

• It raises the possibility of creating 'designer babies'

• It could lead to increased antibiotic resistance

Why have some scientists called for a global pause on the use of CRISPR in human embryos?

• To prevent commercial exploitation

• To focus on animal research first

• To consider the ethical and societal implications

• To allow time for technological improvements

What is a potential non-therapeutic use of CRISPR technology?

• Developing new vaccines

• Creating crops with higher yields

• Producing more efficient solar panels

• Engineering humans with enhanced traits

What is the main concern of those who oppose the immediate use of CRISPR technology?

• It is too difficult to use

• The technology is too expensive

• The potential risks and complications have not been fully considered

• It is not effective enough

How might the discussion around CRISPR technology influence other scientific fields?

• It could lead to increased funding for all scientific research

• It will likely result in stricter regulations for all technologies

• It might serve as a model for addressing ethical concerns in other fields

• It will discourage innovation in other areas

What is the significance of the December meeting mentioned in the transcript?

• To celebrate the achievements of CRISPR scientists

• To announce new CRISPR research findings

• To discuss the responsible use of CRISPR technology

• To finalize the commercial applications of CRISPR