Hemoglobin Function Haldane Effect

The video tutorial explains the Haldane and Bohr effects, focusing on their differences and similarities. The Bohr effect describes how pH levels influence oxygen binding to hemoglobin, while the Haldane effect focuses on the role of CO2 concentration. The tutorial delves into the molecular mechanisms of the Haldane effect, highlighting the roles of lysine and arginine residues. It also discusses the physiological implications of these effects in the lungs and tissues, emphasizing the importance of Le Chatelier's principle in these processes.

What is the primary focus of the Bohr effect?

• How hemoglobin structure affects oxygen binding

• How CO2 affects oxygen binding

• How pH affects oxygen binding

• How temperature affects oxygen binding

According to the Bohr effect, what happens when there is a low pH?

• Hydrogen ions are released from hemoglobin

• CO2 is released from hemoglobin

• Oxygen is released from hemoglobin

• Oxygen binds more tightly to hemoglobin

What does the Haldane effect primarily describe?

• The effect of pH on oxygen binding

• The effect of temperature on oxygen binding

• The effect of hemoglobin structure on oxygen binding

• The effect of CO2 on oxygen binding

In the Haldane effect, what happens when CO2 binds to hemoglobin?

• Oxygen is released

• Oxygen binds more tightly

• CO2 is released

• Hydrogen ions are released

Which amino acid is more likely to bind CO2 in the Haldane effect?

• Arginine

• Lysine

• Histidine

• Glutamine

Why is lysine more reactive in binding CO2 compared to arginine?

• Lysine has a delocalized lone pair

• Lysine has a localized lone pair

• Arginine has a localized lone pair

• Arginine is more abundant

Where does the release of CO2 due to the Haldane effect primarily occur?

• In the brain

• In the lungs

• In the liver

• In the kidneys

What principle governs the Haldane effect?

• Boyle's law

• Avogadro's law

• Le Chatelier's principle

• Charles's law

What happens to CO2 when there is a high influx of oxygen in the lungs?

• Oxygen is released

• CO2 is released and exhaled

• CO2 binds more tightly to hemoglobin

• Hydrogen ions are released

What is the role of metabolically active cells in the Haldane effect?

• They produce oxygen

• They consume CO2

• They produce CO2 as a waste product

• They consume hydrogen ions