Branched Chain Amino Acid Metabolism | BCAA Catabolism | Pathway and Regulation

The video tutorial explains the metabolism and catabolism of branch chain amino acids (BCAAs) such as valine, isoleucine, and leucine. It covers their essential role in the diet, their metabolic pathways, and the enzymes involved, including branch chain amino transferase and branch chain alpha-ketoacid dehydrogenase. The tutorial also discusses the regulation of these processes and the categorization of BCAAs as glucogenic or ketogenic based on their metabolic products. Key regulatory factors like BDK and PTPN 1K are highlighted, along with the importance of cofactors such as vitamin B6 and B12.

Which of the following amino acids is not a branch chain amino acid?

• Glycine

• Leucine

• Isoleucine

• Valine

What is the primary site of branch chain amino acid metabolism?

• Heart

• Kidneys

• Skeletal muscle

• Liver

Which cofactor is required for the transfer of the amino group from BCAAs to alpha ketoglutarate?

• Vitamin B12

• Biotin

• Thiamine pyrophosphate

• Pyridoxal phosphate

What is the role of branch chain ketoacid dehydrogenase kinase (BDK) in BCAA catabolism?

• It removes amino groups from BCAAs

• It activates the BCH complex

• It converts BCAAs into ketoacids

• It inhibits the BCH complex

Which vitamin is necessary for the enzyme methylmalonyl CoA mutase to function?

• Vitamin B12

• Vitamin B7

• Vitamin B6

• Vitamin C

Which BCAA is considered solely ketogenic?

• Glycine

• Leucine

• Valine

• Isoleucine

What is the final product of leucine catabolism that can be used as an energy source?

• Propionyl CoA

• Succinyl CoA

• Alpha-ketoglutarate

• Acetoacetate