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Apoptosis | The Extrinsic Pathway

Apoptosis | The Extrinsic Pathway

Assessment

Interactive Video

•

Science, Biology

•

University

•

Practice Problem

•

Hard

Created by

Wayground Content

FREE Resource

The video tutorial by Kevin Tolkoff explores the intrinsic and extrinsic pathways of apoptosis. It begins with a recap of the mitochondrial (intrinsic) pathway, highlighting the role of mitochondria in apoptosis. The focus then shifts to the extrinsic pathway, which requires external stimuli, often from immune cells. The video details the role of caspases, particularly caspase 8 and 3, in executing apoptosis. It also discusses the crosstalk between the extrinsic and mitochondrial pathways, emphasizing how proteins like bid facilitate this interaction, leading to complete cell death.

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10 questions

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1.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What role does the mitochondria play in the intrinsic pathway of apoptosis?

It activates immune cells.

It repairs DNA damage.

It prevents the release of apoptotic proteins.

It releases proteins that initiate apoptosis.

2.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

Which receptor is involved in the extrinsic pathway of apoptosis?

BCL receptor

FAS receptor

Caspase receptor

Diablo receptor

3.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the function of caspase 8 in the apoptosis process?

It repairs cell membranes.

It acts as an initiator caspase.

It directly degrades DNA.

It inhibits apoptosis.

4.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

How does caspase 3 contribute to apoptosis?

By blocking apoptotic bodies.

By repairing DNA.

By serving as an executioner caspase.

By inhibiting other caspases.

5.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What is the role of IAP in a healthy cell?

It degrades DNA.

It promotes apoptosis.

It inhibits apoptosis.

It activates caspase 8.

6.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

What does the protein Bid do in the apoptosis pathways?

It inhibits the extrinsic pathway.

It links the extrinsic and mitochondrial pathways.

It repairs mitochondrial damage.

It activates immune cells.

7.

MULTIPLE CHOICE QUESTION

30 sec • 1 pt

How does cancer affect the extrinsic pathway of apoptosis?

It activates mitochondrial proteins.

It enhances the expression of FAS inhibitors.

It stops the expression of FAS inhibitors.

It repairs DNA damage.

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