Capsaicin | Biosynthesis, Mechanism, & Metabolism

The video tutorial explores capsaicin, the active ingredient in chili peppers, detailing its biosynthesis, mechanism of action, and effects on the body. Capsaicin is a chemical irritant for mammals but not for birds, aiding in seed dispersion. The biosynthesis involves amino acids like phenylalanine and valine. Capsaicin interacts with TRPV1 ion channels, causing a burning sensation. Chronic exposure can reduce pain perception and influence gene expression, affecting weight management. The metabolism of capsaicin involves liver enzymes, producing antioxidant compounds.

What is capsaicin and where is it primarily found?

What role do birds play in the dispersal of capsaicin-containing seeds?

Describe the biosynthesis pathway of capsaicin.

Explain the mechanism of action of capsaicin in sensory neurons.

What is the Scoville scale and how does it relate to capsaicin?

What are the acute effects of capsaicin on the human body?

How does prolonged exposure to capsaicin affect pain perception?

How does capsaicin affect the expression of pro-inflammatory cytokines?

Discuss the chronic effects of capsaicin on inflammation.

What are the metabolic pathways involved in the elimination of capsaicin?