AKT Signaling Pathway: Regulation by the Insulin Signaling Cascade

The video tutorial explains the insulin signaling pathway, focusing on the AKT pathway's regulation. It covers insulin binding, IRS phosphorylation, PI3K activation, and the roles of PDK1 and mTOR complexes. The tutorial also discusses the regulation of phosphorylation sites by phosphatases, the mechanism of glucose uptake via GLUT4, and the mTORC1 pathway's feedback regulation. The video concludes with a summary and resources for further learning.

Identify the two important phosphorylation sites on AKT and their regulators.

How does AKT influence glucose uptake in insulin-stimulated cells?

What is the relationship between mTOR complex 1 and the insulin signaling pathway?