Methotrexate (Rheumatoid Arthritis Drug)

Methotrexate (Rheumatoid Arthritis Drug)

Assessment

Interactive Video

Biology, Health Sciences, Chemistry

11th Grade - University

Hard

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The video tutorial discusses methotrexate, a non-biologic DMARD used to treat rheumatoid arthritis (RA). Initially developed for cancer, methotrexate was found effective for RA due to its ability to inhibit enzymes involved in inflammation. It functions as a pro drug, converting into an active form that accumulates in cells. Methotrexate's anti-inflammatory effects are mediated through adenosine receptors and inhibition of cytokines. Despite its efficacy, methotrexate has side effects, including potential liver damage and folic acid deficiency. It is crucial to monitor patients and avoid use during pregnancy.

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3 questions

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1.

OPEN ENDED QUESTION

3 mins • 1 pt

Discuss the historical context of methotrexate's use in treating rheumatoid arthritis.

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2.

OPEN ENDED QUESTION

3 mins • 1 pt

Why is it important for patients to take folic acid alongside methotrexate?

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3.

OPEN ENDED QUESTION

3 mins • 1 pt

What distinguishes methotrexate from other non-biologic DMARDs?

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