Creatine Function (2/2): Degradation to Creatinine

The video explains the degradation of creatine and phosphocreatine into creatinine, a nonenzymatic process. Phosphocreatine cyclizes more readily than creatine. Creatinine is excreted via the kidneys. Creatine is replenished through synthesis or diet, with 50% synthesized de novo. Creatine supplementation is proven to enhance phosphocreatine stores, aiding high-intensity exercise.

What are the two main sources of creatine in the average person?

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Discuss the effects of creatine supplementation on athletic performance.

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