Phospholipase C, IP3, DAG, and Ca2+

The video provides a concise overview of phospholipase C, its activation by G protein-coupled receptors, and its role in bio signaling. It explains the structure of phosphatidylinositol 4,5-bisphosphate and the mechanism of phospholipase C, leading to the production of inositol 1,4,5-trisphosphate (IP3) and diacylglycerol. The video also discusses the function of IP3 in calcium signaling and the role of diacylglycerol in activating protein kinase C.

Describe the role of calcium as a cofactor for protein kinase C.

What types of amino acids are specifically phosphorylated by protein kinase C?

How does the activation of phospholipase C relate to G protein-coupled receptors?

What is the overall significance of the signaling pathway involving phospholipase C, IP3, and calcium?